Dominant Driving Forces in Human Telomere Quadruplex Binding-Induced Structural Alterations
نویسندگان
چکیده
منابع مشابه
Dominant Driving Forces in Human Telomere Quadruplex Binding-Induced Structural Alterations.
Recently various pathways of human telomere (ht) DNA folding into G-quadruplexes and of ligand binding to these structures have been proposed. However, the key issue as to the nature of forces driving the folding and recognition processes remains unanswered. In this study, structural changes of 22-mer ht-DNA fragment (Tel22), induced by binding of ions (K(+), Na(+)) and specific bisquinolinium ...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2015
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2015.05.001